Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA helicase activity of PcrA is not required for the displacement of RecA protein from DNA or inhibition of RecA-mediated strand exchange.

Journal of bacteriology - 1 Jun 2007

Anand Syam P, Zheng Haocheng, Bianco Piero R, Leuba Sanford H, Khan Saleem A

Abstract excerpt

PcrA is a conserved DNA helicase present in all gram-positive bacteria. Bacteria lacking PcrA show high levels of recombination. Lethality induced by PcrA depletion can be overcome by suppressor mutations in the recombination genes recFOR. RecFOR proteins load RecA onto single-stranded DNA during recombination. Here we test whether an essential function of PcrA is to interfere with RecA-mediated DNA recombination...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Helicases

Share to DNA, Single-Stranded

Share to Fluorescence Resonance Energy Transfer

Share to Gram-Positive Bacteria

Share to Rec A Recombinases

Share to Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 17449621
DOI: 10.1128/JB.00376-07
PMCID: PMC1913354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA helicase activity of PcrA is not required for the displacement of RecA protein from DNA or inhibition of RecA-mediated strand exchange.PMID 17449621Read ↗

Essential bacterial helicases that counteract the toxicity of recombination proteins.Semantic proximity Read ↗

RecFOR proteins are essential for Pol V-mediated translesion synthesis and mutagenesis.Semantic proximity Read ↗

Molecular design and functional organization of the RecA protein.Semantic proximity Read ↗

Bacillus subtilis PcrA Helicase Removes Trafficking Barriers.Semantic proximity Read ↗

UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli.Semantic proximity Read ↗

Differential requirement for RecFOR pathway components in Thermus thermophilus.Semantic proximity Read ↗

RecFOR function is required for DNA repair and recombination in a RecA loading-deficient recB mutant of Escherichia coli.Semantic proximity Read ↗

RecA-dependent mutants in Escherichia coli reveal strategies to avoid chromosomal fragmentation.Semantic proximity Read ↗

PcrA is an essential DNA helicase of Bacillus subtilis fulfilling functions both in repair and rolling-circle replication.Semantic proximity Read ↗

recA mutants of E. coli K12: a personal turning point.Semantic proximity Read ↗

Single Strand Annealing Plays a Major Role in RecA-Independent Recombination between Repeated Sequences in the Radioresistant Deinococcus radiodurans Bacterium.Semantic proximity Read ↗

An improved recombineering approach by adding RecA to lambda Red recombination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.