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Article

PcrA is an essential DNA helicase of Bacillus subtilis fulfilling functions both in repair and rolling-circle replication.

Molecular microbiology - 1 Jul 1998

Petit M A, Dervyn E, Rose M, Entian K D, McGovern S, Ehrlich S D, Bruand C

Abstract excerpt

The only DNA helicase essential for Escherichia coli viability is DnaB, the chromosome replication for helicase. In contrast, in Bacillus subtilis, in addition to the DnaB counterpart called DnaC, we have found a second essential DNA helicase, called PcrA. It is 40% identical to the Rep and UvrD DNA helicases of E. coli and 61% identical to the PcrA helicase of Staphylococcus aureus. This gene is located at 55...

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Identifiers

PMID: 9701819
DOI: 10.1046/j.1365-2958.1998.00927.x

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