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Article

A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity.

Clinical immunology (Orlando, Fla.) - 1 Jun 2007

Yun Gong, Tolar Jakub, Yerich Anton K, Marsh Steven G E, Robinson James, Noreen Harriet, Blazar Bruce R, Miller Jeffrey S

Abstract excerpt

Studies have shown that KIR-ligand mismatching to predict NK cell alloreactivity may result in less relapse and better survival in patients with AML. KIR-ligands are distinguished by single nucleotide polymorphisms (SNPs) from HLA-B and HLA-C sequences. We hypothesized that pyrosequencing to determine KIR-ligand status by direct sequencing of the ligand epitope can be done as an alternative to high-resolution...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17446137
DOI: 10.1016/j.clim.2007.01.011
PMCID: PMC1991282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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