Article
Practical Considerations and Workflow in Utilizing KIR Genotyping in Transplantation Medicine.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022
Yawata Makoto, Yawata Nobuyo
Abstract excerpt
This chapter is intended to serve as a practical guide for establishing a workflow using sequence-specific polymorphism PCR (SSP-PCR) for killer cell immunoglobulin-like receptor (KIR) genotyping in a clinical setting, especially in allogeneic hematopoietic stem cell transplantation (HSCT). As clinical evidence accumulates on the application of KIR and HLA genetics to guide donor selection in HSCT, there is an...
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