Article
NK-KIR ligand identification: a quick Q-PCR approach for HLA-C epitope typing.
Tissue antigens - 1 Apr 2007
Schellekens J, Rozemuller E H, Borst H P E, Otten H G, van den Tweel J G, Tilanus M G J
Abstract excerpt
Interaction of donor natural killer (NK)-cell-associated killer cell immunoglobulin-like receptors (KIRs) with the patient's human leukocyte antigen-C (HLA-C) ligands can result in an alloreactive NK response after haematopoietic stem cell transplantation. In many retrospective studies, additional HLA-C-typing data are required to predict NK-cell alloreactivity. We developed a Taqman assay using the quantitative...
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