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Article

A novel rapid single nucleotide polymorphism (SNP)-based method for assessment of hematopoietic chimerism after allogeneic stem cell transplantation.

Blood - 1 Jan 2003

Hochberg Ephraim P, Miklos David B, Neuberg Donna, Eichner Daniel A, McLaughlin Stephen F, Mattes-Ritz Alex, Alyea Edwin P, Antin Joseph H, Soiffer Robert J, Ritz Jerome

Abstract excerpt

A major end point of nonmyeloablative hematopoietic stem cell transplantation is the attainment of either mixed chimerism or full donor hematopoiesis. Because the majority of human genetic disparity is generated by single nucleotide polymorphisms (SNPs), direct measurement of SNPs should provide a robust tool for the detection and quantitation of chimerism. Using pyrosequencing, a rapid quantitative sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12393452
DOI: 10.1182/blood-2002-05-1365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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