Article
An improved method for HLA-B and -C supratyping.
Journal of immunological methods - 1 Nov 2015
Biassoni R, Malnati M, Vanni I, Raso A, Sironi F, Broccolo F, Garbarino L, Mazzocco M, Montera M, Larghero P, Di Marco E, Ugolotti E
Abstract excerpt
A growing body of evidence links the analysis of the KIR genotype and the presence of their HLA-B and -C ligands to a wide repertoire of human diseases. We noticed that, using a panel of 184 Caucasoid donors, a limited number of HLA alleles were incorrectly supratyped by previously described pyrosequence-based assays. Here we describe a simple implementation of the reported methods that corrects all the...
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