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Article

A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex.

The Journal of experimental medicine - 1 Dec 1991

Mellins E, Kempin S, Smith L, Monji T, Pious D

Abstract excerpt

We have previously described a set of mutants (16.23-selected mutants) of a B lymphoblastoid cell line that are defective in the presentation of intact proteins to class II-restricted T cells, but effectively present immunogenic peptides. The mutations in these mutants are recessive in somatic cell hybrids and are not in Class II structural genes. Here, we report on a unique mutant, 5.2.4, in which a similar...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, MHC Class II

Share to Histocompatibility Antigens Class II

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Source

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Identifiers

PMID: 1744588
DOI: 10.1084/jem.174.6.1607
PMCID: PMC2119029

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Source receipt: pubmed, retrieved 7 Sept 2026.

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