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Article

Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2007

Ivison Sabine M, Graham Nicholas R, Bernales Cecily Q, Kifayet Arnawaz, Ng Natalie, Shobab Leila A, Steiner Theodore S

Abstract excerpt

Protein kinase D (PKD), also called protein kinase C (PKC)mu, is a serine-threonine kinase that is involved in diverse areas of cellular function such as lymphocyte signaling, oxidative stress, and protein secretion. After identifying a putative PKD phosphorylation site in the Toll/IL-1R domain of TLR5, we explored the role of this kinase in the interaction between human TLR5 and enteroaggregative Escherichia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17442957
DOI: 10.4049/jimmunol.178.9.5735

Genes

TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin.PMID 17442957Read ↗

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