Article
Functional characterization of chicken TLR5 reveals species-specific recognition of flagellin.
Molecular immunology - 1 Mar 2008
Keestra A Marijke, de Zoete Marcel R, van Aubel Rémon A M H, van Putten Jos P M
Abstract excerpt
Mammalian Toll-like receptor 5 (TLR5) senses flagellin of several bacterial species and activates the innate immune system. The avian TLR repertoire exhibits considerable functional diversity compared to mammalian TLRs and evidence of a functional TLR5 in the avian species is lacking. In the pres...
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