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Article

Clostridium difficile flagella predominantly activate TLR5-linked NF-κB pathway in epithelial cells.

Anaerobe - 1 Apr 2016

Batah Jameel, Denève-Larrazet Cécile, Jolivot Pierre-Alain, Kuehne Sarah, Collignon Anne, Marvaud Jean-Christophe, Kansau Imad

Abstract excerpt

Clostridium difficile has become the most common enteropathogen responsible for intestinal nosocomial post-antibiotic infections. This has coincided with the appearance of serious cases related to the emergence of hypervirulent strains. The toxins are the main virulence factors and elicit an inflammatory response during C. difficile infection. However, other bacterial components appear to be involved in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26790921
DOI: 10.1016/j.anaerobe.2016.01.002

Genes

TLR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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