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Article

Activation of the proteinase B precursor of the yeast Saccharomyces cerevisiae by autocatalysis and by an internal sequence.

The Journal of biological chemistry - 5 Dec 1991

Nebes V L, Jones E W

Abstract excerpt

Proteinase B (PrB) is a subtilisin-like serine protease found in the vacuole of the yeast Saccharomyces cerevisiae. It is first made as a large precursor that consists of a putative signal sequence, a 260-amino acid pro region, the serine protease domain, and two small COOH-terminal post regions (Moehle, C. M., Dixon, C. K., and Jones, E. W. (1989) J. Cell Biol. 108, 309-324). This precursor is glycosylated and...

Topics

Base Sequence
Catalysis
DNA, Fungal
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Molecular Sequence Data
Mutation
Protein Precursors
Protein Processing, Post-Translational
Saccharomyces cerevisiae

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Serine Endopeptidases

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PMID: 1744078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1744078-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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