Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae.

Abstract excerpt

Pyruvate decarboxylase is the key enzyme in alcoholic fermentation in yeast. Two structural genes, PDC1 and PDC5 have been characterized. Deletion of either of these genes has little or no effect on the specific pyruvate decarboxylase activity, but enzyme activity is undetectable in mutants lacking both PDC1 and PDC5 (S. Hohmann and H. Cederberg, Eur. J. Biochem. 188:615-621, 1990). Here I describe PDC6, a gene...

Topics

• Amino Acid Sequence
• Blotting, Northern
• Blotting, Southern
• Genes, Fungal
• Molecular Sequence Data
• Mutation
• Pyruvate Decarboxylase
• Saccharomyces cerevisiae
• Sequence Alignment
• Spores, Fungal