Article
Autoregulation may control the expression of yeast pyruvate decarboxylase structural genes PDC1 and PDC5.
European journal of biochemistry - 30 Mar 1990
Hohmann S, Cederberg H
Abstract excerpt
Recently we deleted the pyruvate decarboxylase structural gene PDC1 from the genome of the yeast Saccharomyces cerevisiae. The pdc1 deletion mutants had pyruvate decarboxylase activity due to the presence of a second structural gene [Schaaff, I., Green, J. B. A., Gozalbo, D. & Hohmann, S. (1989) Curr. Genet. 15, 75-81]. We cloned and sequenced this gene which we call PDC5. The predicted amino acid sequences of...
Read the complete abstract on PubMedTopics
- Alleles
- Amino Acid Sequence
- Carboxy-Lyases
- Chromosome Deletion
- Cloning, Molecular
- Enzyme Activation
- Gene Expression Regulation, Enzymologic
