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Article

Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast.

Genetics - 1 Mar 1997

Velmurugan S, Lobo Z, Maitra P K

Abstract excerpt

Mutants lacking pyruvate decarboxylase cannot grow on glucose. We have isolated three different complementation groups of extragenic suppressors that suppress mutations in pdc2, a regulatory locus required for the synthesis of the glycolytic enzyme pyruvate decarboxylase. The most frequent of these is a recessive mutation in the structural gene PFK1 of the soluble phosphofructokinase. The other class XSP18...

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Identifiers

PMID: 9055069
DOI: 10.1093/genetics/145.3.587
PMCID: PMC1207844

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Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast.PMID 9055069Read ↗

Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae.Semantic proximity Read ↗

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Autoregulation of yeast pyruvate decarboxylase gene expression requires the enzyme but not its catalytic activity.Semantic proximity Read ↗

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