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Article

Autoregulation of yeast pyruvate decarboxylase gene expression requires the enzyme but not its catalytic activity.

European journal of biochemistry - 1 May 1999

Eberhardt I, Cederberg H, Li H, König S, Jordan F, Hohmann S

Abstract excerpt

In the yeast, Saccharomyces cerevisiae, pyruvate decarboxylase (Pdc) is encoded by the two isogenes PDC1 and PDC5. Deletion of the more strongly expressed PDC1 gene stimulates the promoter activity of both PDC1 and PDC5, a phenomenon called Pdc autoregulation. Hence, pdc1Delta strains have high Pdc specific activity and can grow on glucose medium. In this work we have characterized the mutant alleles pdc1-8 and...

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Source

Identifiers

PMID: 10231381
DOI: 10.1046/j.1432-1327.1999.00370.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Autoregulation of yeast pyruvate decarboxylase gene expression requires the enzyme but not its catalytic activity.PMID 10231381Read ↗

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