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Article

PDC6, a weakly expressed pyruvate decarboxylase gene from yeast, is activated when fused spontaneously under the control of the PDC1 promoter.

Current genetics - 1 Nov 1991

Hohmann S

Abstract excerpt

Three structural genes encode the pyruvate decarboxylase isoenzymes in the yeast Saccharomyces cerevisiae. PDC1 and PDC5 are active during glucose fermentation where PDC1 is expressed about six times more strongly than PDC5. Expression of PDC6 is weak and seems to be induced in ethanol medium. Consequently, pdc1 delta pdc5 delta double mutants do not ferment glucose and do not grow on glucose medium. Spontaneous...

Topics

Alleles
Amino Acid Sequence
Blotting, Northern
Codon
Gene Expression Regulation, Fungal
Glucose
Isoenzymes
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Pyruvate Decarboxylase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Restriction Mapping

Saccharomyces cerevisiae

Source

Identifiers

PMID: 1807827
DOI: 10.1007/BF00317064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1807827-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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PDC6, a weakly expressed pyruvate decarboxylase gene from yeast, is activated when fused spontaneously under the control of the PDC1 promoter.PMID 1807827Read ↗

pdc1(0) mutants of Saccharomyces cerevisiae give evidence for an additional structural PDC gene: cloning of PDC5, a gene homologous to PDC1.Semantic proximity Read ↗

Characterization of PDC6, a third structural gene for pyruvate decarboxylase in Saccharomyces cerevisiae.Semantic proximity Read ↗

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