Article
Loop II of DNA polymerase beta is important for polymerization activity and fidelity.
Nucleic acids research - 1 Jan 2007
Lin George C, Jaeger Joachim, Sweasy Joann B
Abstract excerpt
The accurate replication and transmission of genetic information is critical in the life of an organism. During its entire lifespan, the genetic information is constantly under attack from endogenous and exogenous sources of damage. To ensure that the content of its genetic information is faithfully preserved for synthesis and transmission, eukaryotic cells have developed a complex system of genomic quality...
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