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Pivotal role of the beta-clamp in translesion DNA synthesis and mutagenesis in E. coli cells.

DNA repair - 4 Sept 2002

Becherel Olivier J, Fuchs Robert P P, Wagner Jérôme

Abstract excerpt

The genetic information is continuously subjected to the attack by endogenous and exogenous chemical and physical carcinogens that damage the DNA template, thus compromising its biochemical functions. Despite the multiple and efficient DNA repair systems that have evolved to cope with the large variety of damages, some lesions may persist and, as a consequence, interfere with DNA replication. By essence, the...

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Identifiers

PMID: 12509274
DOI: 10.1016/s1568-7864(02)00106-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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