Article
Measuring European population stratification with microarray genotype data.
American journal of human genetics - 1 May 2007
Bauchet Marc, McEvoy Brian, Pearson Laurel N, Quillen Ellen E, Sarkisian Tamara, Hovhannesyan Kristine, Deka Ranjan, Bradley Daniel G, Shriver Mark D
Abstract excerpt
A proper understanding of population genetic stratification--differences in individual ancestry within a population--is crucial in attempts to find genes for complex traits through association mapping. We report on genomewide typing of approximately 10,000 single-nucleotide polymorphisms in 297 individuals, to explore population structure in Europeans of known and unknown ancestry. The results reveal the presence...
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