Article
European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups.
Molecular medicine (Cambridge, Mass.) - 1 Jan 2000
Tian Chao, Kosoy Roman, Nassir Rami, Lee Annette, Villoslada Pablo, Klareskog Lars, Hammarström Lennart, Garchon Henri-Jean, Pulver Ann E, Ransom Michael, Gregersen Peter K, Seldin Michael F
Abstract excerpt
The definition of European population genetic substructure and its application to understanding complex phenotypes is becoming increasingly important. In the current study using over 4,000 subjects genotyped for 300,000 single-nucleotide polymorphisms (SNPs), we provide further insight into relationships among European population groups and identify sets of SNP ancestry informative markers (AIMs) for application...
Topics
- Europe
- Genetic Markers
- Genetics, Population
- Genome-Wide Association Study
- Humans
- Polymorphism, Single Nucleotide
- Principal Component Analysis
- White People