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Article

Genetic liability to schizophrenia in Oceanic Palau: a search in the affected and maternal generation.

Human genetics - 1 Jul 2007

Devlin Bernie, Klei Lambertus, Myles-Worsley Marina, Tiobech Josepha, Otto Caleb, Byerley William, Roeder Kathryn

Abstract excerpt

While liability to schizophrenia (Scz) is due to genetic and environmental factors, specific factors are largely unknown. We postulate a two-hit model for Scz, in which initial liability is generated during fetal brain development: this "hit" is precipitated by environmental stressors biologically interacting with maternal genetic vulnerability to the stress. Additional liability to Scz is generated by individual...

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Identifiers

PMID: 17436020
DOI: 10.1007/s00439-007-0358-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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