Article
Nature and nurture interplay: schizophrenia.
Psychiatrische Praxis - 1 Nov 2004
McGuffin Peter
Abstract excerpt
There is compelling evidence from family, twin and adoption studies of a substantial genetic contribution to schizophrenia. The mode of transmission is complicated and very rarely if ever involves a single gene. Rather schizophrenia results from multiple genes of small effect and their interplay with the environment. Perhaps because the overall size of the genetic effect is large, accounting for about 80 % of...
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