Article
Copy number variants for schizophrenia and related psychotic disorders in Oceanic Palau: risk and transmission in extended pedigrees.
Biological psychiatry - 15 Dec 2011
Melhem Nadine, Middleton Frank, McFadden Kathryn, Klei Lambertus, Faraone Stephen V, Vinogradov Sophia, Tiobech Josepha, Yano Victor, Kuartei Stevenson, Roeder Kathryn, Byerley William, Devlin Bernie, Myles-Worsley Marina
Abstract excerpt
BACKGROUND: We report on copy number variants (CNVs) found in Palauan subjects ascertained for schizophrenia and related psychotic disorders in extended pedigrees in Palau. We compare CNVs found in this Oceanic population with those seen in other samples, typically of European ancestry. Assessing CNVs in Palauan extended pedigrees yields insight into the evolution of risk CNVs, such as how they arise, are...
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