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Article

Genome-wide screening of loci associated with drug resistance to 5-fluorouracil-based drugs.

Cancer science - 1 Apr 2007

Ooyama Akio, Okayama Yoshihiro, Takechi Teiji, Sugimoto Yoshikazu, Oka Toshinori, Fukushima Masakazu

Abstract excerpt

Resistance to chemotherapeutic agents represents the chief cause of mortality in cancer patients with advanced disease. Chromosomal aberration and altered gene expression are the main genetic mechanisms of tumor chemoresistance. In this study, we have established an algorithm to calculate DNA copy number using the Affymetrix 10K array, and performed a genome-wide correlation analysis between DNA copy number and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17425594
DOI: 10.1111/j.1349-7006.2007.00424.x
PMCID: PMC11158905

Genes

TYMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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