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Article

Copy number polymorphisms and anticancer pharmacogenomics.

Genome biology - 1 Jan 2011

Gamazon Eric R, Huang R Stephanie, Dolan M Eileen, Cox Nancy J

Abstract excerpt

BACKGROUND: Recent studies have investigated the contribution of copy number variants (CNVs) to disease susceptibility in a multitude of complex disorders, including systemic lupus erythematosus, Crohn's disease, and various neurodevelopmental disorders. Relatively few CNV studies, however, have been conducted on pharmacologic phenotypes even though these structural variants are likely to play an important role....

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Identifiers

PMID: 21609475
DOI: 10.1186/gb-2011-12-5-r46
PMCID: PMC3219969

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