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Article

QSAR of multiple mutated antibodies.

Journal of molecular recognition : JMR - 1 Jan 2000

Mandrika Ilona, Prusis Peteris, Yahorava Sviatlana, Tars Kaspars, Wikberg Jarl E S

Abstract excerpt

The aim of this study was to develop predictive quantitative structure-activity relationship (QSAR) modeling for antibody-peptide interactions. A small single chain antibody library was designed and manufactured around the murine anti-p24 (HIV-1) monoclonal antibody CB4-1 by use of statistical molecular design (SMD) principles and site directed mutagenesis, and its affinity for a p24 derived antigen was...

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Share to Antibodies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17421049
DOI: 10.1002/jmr.817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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