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Article

Predicting antibody affinity changes upon mutations by combining multiple predictors.

Scientific reports - 11 Nov 2020

Kurumida Yoichi, Saito Yutaka, Kameda Tomoshi

Abstract excerpt

Antibodies are proteins working in our immune system with high affinity and specificity for target antigens, making them excellent tools for both biotherapeutic and bioengineering applications. The prediction of antibody affinity changes upon mutations ([Formula: see text]) is important for antibody engineering. Numerous computational methods have been proposed based on different approaches including molecular...

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Identifiers

PMID: 33177627
DOI: 10.1038/s41598-020-76369-8
PMCID: PMC7658247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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