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Article

Proteochemometric modelling of antibody-antigen interactions using SPOT synthesised peptide arrays.

Protein engineering, design & selection : PEDS - 1 Jun 2007

Mandrika Ilona, Prusis Peteris, Yahorava Sviatlana, Shikhagaie Medya, Wikberg Jarl E S

Abstract excerpt

Proteochemometrics is a technology for the study of molecular recognition based on chemometric techniques. Here we applied it to analyse the amino acids and amino acid physico-chemical properties that are involved in antibodies' recognition of peptide antigens. To this end, we used a study system comprised by a diverse single chain antibody library derived from the murine mAb anti-p24 (HIV-1) antibody CB4-1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17588963
DOI: 10.1093/protein/gzm022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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