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Article

Computer-aided antibody design

2 Jun 2012

Abstract excerpt

Recent clinical trials using antibodies with low toxicity and high efficiency have raised expectations for the development of next-generation protein therapeutics. However, the process of obtaining therapeutic antibodies remains time consuming and empirical. This review summarizes recent progresses in the field of computer-aided antibody development mainly focusing on antibody modeling, which is divided...

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Share to Glycosylation and Glycoproteins Research
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Identifiers

PMID: 22661385
DOI: 10.1093/protein/gzs024

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