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Article

Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer.

International journal of cancer - 1 Aug 2007

Schafmayer Clemens, Buch Stephan, Egberts Jan Hendrik, Franke Andre, Brosch Mario, El Sharawy Abdou, Conring Mareike, Koschnick Maralde, Schwiedernoch Sven, Katalinic Alexander, Kremer Bernd, Fölsch Ulrich R, Krawczak Michael, Fändrich Fred, Schreiber Stefan, Tepel Jürgen, Hampe Jochen

Abstract excerpt

Mutations in DNA repair genes have previously been identified as causative factors for hereditary nonpolyposis colon cancer (HNPCC). Recent evidence also supports an association between DNA sequence variation in these genes and sporadic colorectal carcinoma (CRC). Genetic investigation of DNA repair genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1, as possible susceptibility factors for sporadic CRC, was done...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17417778
DOI: 10.1002/ijc.22735

Genes

MLH1
OGG1
MSH2
MSH6
MUTYH
PMS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer.PMID 17417778Read ↗

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