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Article

A MLH1 polymorphism that increases cancer risk is associated with better outcome in sporadic colorectal cancer.

Cancer genetics and cytogenetics - 1 Sept 2009

Nejda Nargisse, Iglesias Daniel, Moreno Azcoita Mariano, Medina Arana Vicente, González-Aguilera Juan J, Fernández-Peralta Antonia M

Abstract excerpt

Germline mutations or the malfunctioning of postreplicative mismatch repair genes (MMR) are responsible of hereditary nonpolyposis colorectal cancer (HNPCC), and are also implied in some sporadic colorectal cancer (CRC) forms without any familial history of this disease. Besides germinal mutations and methylation, single-nucleotide polymorphisms (SNP) can predispose to nonfamilial CRC with low to moderate...

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Identifiers

PMID: 19665066
DOI: 10.1016/j.cancergencyto.2009.04.011

Genes

MLH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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