Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of MYH polymorphisms in sporadic colorectal cancer in China: a case-control, population-based study.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Yang Liu, Huang Xin-En, Xu Lin, Zhou Jian-Nong, Yu Dong-Sheng, Zhou Xin, Li Dong-Zheng, Guan Xin

Abstract excerpt

PURPOSE: Biallelic germline variants of the 8-hydroxyguanine (8-OG) repair gene MYH have been associated with colorectal neoplasms that display somatic G:C?T:A transversions. However, the effect of single germline variants has not been widely studied, prompting the present investigation of monoallelic MYH variants and susceptibility to sporadic colorectal cancer (CRC) in a Chinese population. PATIENTS AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to DNA Glycosylases

Share to Germ-Line Mutation

Share to Heterozygote

Share to Loss of Heterozygosity

Source

Identifiers

PMID: 24377541
DOI: 10.7314/apjcp.2013.14.11.6403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of MYH polymorphisms in sporadic colorectal cancer in China: a case-control, population-based study.PMID 24377541Read ↗

Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study.Semantic proximity Read ↗

Role of inherited defects of MYH in the development of sporadic colorectal cancer.Semantic proximity Read ↗

Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk.Semantic proximity Read ↗

Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study.Semantic proximity Read ↗

The role of MYH gene in genetic predisposition to colorectal cancer: another piece of the puzzle.Semantic proximity Read ↗

Colorectal Cancer Risk in Monoallelic Carriers of MYH VariantsSemantic proximity Read ↗

Mutational analysis of OGG1, MYH, MTH1 in FAP, HNPCC and sporadic colorectal cancer patients: R154H OGG1 polymorphism is associated with sporadic colorectal cancer patients.Semantic proximity Read ↗

Germline mutations and polymorphic variants in MMR, E-cadherin and MYH genes associated with familial gastric cancer in Jiangsu of China.Semantic proximity Read ↗

Germline Mutations but Not Somatic Changes at the MYH Locus Contribute to the Pathogenesis of Unselected Colorectal CancersSemantic proximity Read ↗

Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations.Semantic proximity Read ↗

Microsatellite stable colorectal cancers in clinically suspected hereditary nonpolyposis colorectal cancer patients without vertical transmission of disease are unlikely to be caused by biallelic germline mutations in MYH.Semantic proximity Read ↗

A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.