Article
Chemokine receptor 5 and primary biliary cirrhosis: a two-centre genetic association study.
Liver international : official journal of the International Association for the Study of the Liver - 1 Dec 2004
Baragiotta A, Floreani A, Agarwal K, Venturi C, Craggs A, Jones D E J, Donaldson P T, Bassendine M F
Abstract excerpt
BACKGROUND: Chemokines and their receptors are important mediators of leucocyte trafficking and are suggested to be critical for establishment of inflammatory autoimmune processes. CC chemokine receptor 5 (CCR5) is expressed preferentially by CD4+ T cells. We hypothesised that the CCR5delta(Delta...
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