Article
Fecal multiple molecular tests to detect colorectal cancer in stool.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Sept 2003
Calistri Daniele, Rengucci Claudia, Bocchini Renato, Saragoni Luca, Zoli Wainer, Amadori Dino
Abstract excerpt
BACKGROUND & AIMS: Evaluation of molecular alterations in fecal DNA is a potential, noninvasive, alternative tool for the detection of colorectal cancer. We analyzed a large panel of molecular alterations involved in tumor transformation and progression to define their single diagnostic contribution in terms of sensitivity, cost, and time required to carry out the different tests. METHODS: DNA was analyzed in...
Topics
- Adult
- Aged
- Aged, 80 and over
- Biomarkers
- Colorectal Neoplasms
- DNA, Neoplasm
- Feces
- Female
- Genes, APC
- Genes, p53
- Genes, ras
