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Article

Frequent detection of K-ras mutation in stool samples of colorectal carcinoma patients after improved DNA extraction: comparison with tissue samples.

International journal of oncology - 1 Jun 2002

Ito Yasushi, Kobayashi Susumu, Taniguchi Tetsushi, Kainuma Osamu, Hara Tsuyosi, Ochiai Takenori

Abstract excerpt

Fecal occult blood testing is widely used in the clinical screening of colorectal tumors. However, this method has so frequent false-positive results that more accurate screening-strategy should be established. Although the molecular screening using K-ras gene mutation in stools has been attempted to improve the results, the low rate of DNA extraction from stools leaves this measurement under utility value. In...

Topics

Aged
Base Sequence
Colorectal Neoplasms
DNA, Neoplasm
Feces
Female
Genes, ras
Humans
Male
Middle Aged
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

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Identifiers

PMID: 12012008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12012008-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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