Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Field-based evidence for the linkage of pfcrt and pfdhfr drug-resistant malaria genotypes and clinical profiles of severe malaria in Niger.

Microbes and infection - 1 Apr 2007

Ibrahim Maman Laminou, Gay-Andrieu Françoise, Adehossi Eric, Lacroix Veronique, Randrianarivelojosia Milijaona, Duchemin Jean-Bernard

Abstract excerpt

Drug resistance has been shown to increase malaria mortality and morbidity in both community- and hospital-based studies. We investigated the association between two Plasmodium falciparum drug resistance-related molecular markers and clinical profiles of severe malaria in children hospitalised in Niger. PCR-RFLP analysis showed that the codon 108 mutation of the pfdhfr gene was positively linked to severe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Infant

Share to Malaria, Falciparum

Share to Membrane Transport Proteins

Share to Plasmodium falciparum

Share to Protozoan Proteins

Source

Identifiers

PMID: 17409009
DOI: 10.1016/j.micinf.2007.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Field-based evidence for the linkage of pfcrt and pfdhfr drug-resistant malaria genotypes and clinical profiles of severe malaria in Niger.PMID 17409009Read ↗

Genetic markers associated with antimalarial drug resistance and haemoglobin genotypes among malaria patients in Kaduna State, NigeriaSemantic proximity Read ↗

Prevalence of Mutations in the Pfdhfr, Pfdhps, and Pfmdr1 Genes of Malarial Parasites Isolated from Symptomatic Patients in Dogondoutchi, NigerSemantic proximity Read ↗

Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola.Semantic proximity Read ↗

Molecular markers for drug resistance in malaria: use in treatment, diagnosis and epidemiologySemantic proximity Read ↗

Drug resistance-virulence relationship in Plasmodium falciparum causing severe malaria in an area of seasonal and unstable transmission.Semantic proximity Read ↗

Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in Niger.Semantic proximity Read ↗

Associations between Aminoquinoline Resistance Genotypes and Clinical Presentations of Plasmodium falciparum Infection in Uganda.Semantic proximity Read ↗

Genetics of chloroquine-resistant malaria: a haplotypic viewSemantic proximity Read ↗

Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda.Semantic proximity Read ↗

A Molecular Marker for Chloroquine-Resistant Falciparum MalariaSemantic proximity Read ↗

Polymorphism of PfATPase in Niger: detection of three new point mutationsSemantic proximity Read ↗

Genetic and biochemical aspects of drug resistance in malaria parasites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.