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Article

Drug resistance-virulence relationship in Plasmodium falciparum causing severe malaria in an area of seasonal and unstable transmission.

Acta tropica - 1 Feb 2006

Giha Hayder A, Elbashir Mustafa I, A-Elbasit Ishraga E, A-Elgadir Thoraya M E, ElGhazali Gehad E, Mackinnon Margaret J, Babiker Hamza A

Abstract excerpt

The pathogenesis of severe Plasmodium falciparum malaria is still obscure, but is believed to be multi-factorial, and among the important factors are intrinsic parasite-properties. Here we investigated the association between clinical manifestation of P. falciparum malaria (an indicator of virulence) and two parasite properties--drug resistance and gametocyte production. Among 996 P. falciparum infections...

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PMID: 16336938
DOI: 10.1016/j.actatropica.2005.10.004

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