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Article

Associations between Aminoquinoline Resistance Genotypes and Clinical Presentations of Plasmodium falciparum Infection in Uganda.

Antimicrobial agents and chemotherapy - 21 Sept 2020

Cuu Gloria, Asua Victor, Tukwasibwe Stephen, Nsobya Sam L, Nanteza Ann, Kimuda Magambo Phillip, Mpimbaza Arthur, Rosenthal Philip J

Abstract excerpt

Mutations that mediate resistance of Plasmodium falciparum to aminoquinoline antimalarials are selected by prior drug use and may alter parasite fitness, but associations with clinical presentations are uncertain. We evaluated genotypes in samples from a case-control study of determinants of severe malaria in Ugandan children 4 months to 10 years of age. We studied 274 cases with severe malaria matched by age and...

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Identifiers

PMID: 32660999
DOI: 10.1128/AAC.00721-20
PMCID: PMC7508615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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