Article
Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola.
Malaria journal - 17 Nov 2008
Figueiredo Paula, Benchimol Carla, Lopes Dinora, Bernardino Luís, do Rosário Virgílio E, Varandas Luís, Nogueira Fátima
Abstract excerpt
BACKGROUND: Malaria is the infectious disease causing the highest morbidity and mortality in Angola and due to widespread chloroquine (CQ) resistance, the country has recently changed its first-line treatment recommendations for uncomplicated malaria, from CQ to artemisinin combination therapies (ACT) in adults, and sulphadoxine/pyrimethamine (S/P) in pregnant women. Loss of SP sensitivity is, however,...
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