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Article

TGF-betaRII rescues development of small intestinal epithelial cells in Elf3-deficient mice.

Gastroenterology - 1 Apr 2007

Flentjar Nicole, Chu Po-Yin, Ng Annie Y-N, Johnstone Cameron N, Heath Joan K, Ernst Matthias, Hertzog Paul J, Pritchard Melanie A

Abstract excerpt

BACKGROUND & AIMS: ELF3, a member of the ETS transcription factor family, has been shown to transactivate the transforming growth factor beta type II receptor (TGF-betaRII) promoter. Previously we showed that Elf3-null mice have a defect in the small intestine caused by a failure of small intestinal epithelial cells to differentiate and that these cells produced significantly lower levels of Tgf-betaRII. To prove...

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Source

Identifiers

PMID: 17408644
DOI: 10.1053/j.gastro.2007.02.054

Genes

ELF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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