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Article

Fibroblast growth factor receptor-3 regulates Paneth cell lineage allocation and accrual of epithelial stem cells during murine intestinal development.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jul 2009

Vidrich Alda, Buzan Jenny M, Brodrick Brooks, Ilo Chibuzo, Bradley Leigh, Fendig Kirstin Skaar, Sturgill Thomas, Cohn Steven M

Abstract excerpt

Fibroblast growth factor receptor 3 (FGFR-3) is expressed in the lower crypt epithelium, where stem cells of the intestine reside. The role of FGFR-3 signaling in regulating features of intestinal morphogenesis was examined in FGFR-3-null (FGFR-3(-/-)) mice. FGFR-3(-/-) mice had only about half t...

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Identifiers

PMID: 19407216
DOI: 10.1152/ajpgi.90589.2008
PMCID: PMC2711760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19407216-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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