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Article

Analyses of Gnai3-iresGFP reporter mice reveal unknown Gαi3 expression sites.

Scientific reports - 12 Jul 2021

Leiss Veronika, Reisinger Ellen, Speidel Annika, Beer-Hammer Sandra, Nürnberg Bernd

Abstract excerpt

Inhibitory G proteins (Gi proteins) are highly homologous but play distinct biological roles. However, their isoform-specific detection remains challenging. To facilitate the analysis of Gαi3 expression, we generated a Gnai3- iresGFP reporter mouse line. An internal ribosomal entry site (IRES) was inserted behind the stop-codon of the Gnai3 gene to initiate simultaneous translation of the GFP cDNA together...

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Identifiers

PMID: 34253772
DOI: 10.1038/s41598-021-93591-0
PMCID: PMC8275620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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