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Article

Genetic targeting of relaxin and insulin-like factor 3 receptors in mice.

Endocrinology - 1 Oct 2004

Kamat Aparna A, Feng Shu, Bogatcheva Natalia V, Truong Anne, Bishop Colin E, Agoulnik Alexander I

Abstract excerpt

Relaxin (RLN) is a small peptide hormone that affects a variety of biological processes. Rln1 knockout mice exhibit abnormal nipple development, prolonged parturition, agerelated pulmonary fibrosis, and abnormalities in the testes and prostate. We describe here RLN receptor Lgr7-deficient mice. Mutant females have grossly underdeveloped nipples and are unable to feed their progeny. Some Lgr7-/- females were...

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Identifiers

PMID: 15256493
DOI: 10.1210/en.2004-0515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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