Article
Generation of mice with a conditional allele for Trim33.
Genesis (New York, N.Y. : 2000) - 1 Jun 2008
Kim Jieun, Kaartinen Vesa
Abstract excerpt
Trim33 (Tif1gamma, ectodermin, moonshine), a member of the TIF1 family of transcriptional coactivators and corepressors, is a large nuclear protein that contains an N-terminal tripartite (Trim) domain composed of a RING domain, two B-box domains, and a coiled coil domain. It has been suggested that Trim33 (Ectodermin) mediates ectodermal induction in the Xenopus by functioning as a Smad4 ubiquitin ligase, while...
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