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Article

Daptomycin nonsusceptibility in Staphylococcus aureus with reduced vancomycin susceptibility is independent of alterations in MprF.

Antimicrobial agents and chemotherapy - 1 Jun 2007

Pillai Satish K, Gold Howard S, Sakoulas George, Wennersten Christine, Moellering Robert C, Eliopoulos George M

Abstract excerpt

A previous study documented the presence of mutations in mprF that accompanied the loss of daptomycin susceptibility among Staphylococcus aureus isolates following exposure to the drug. An association between the development of glycopeptide-intermediate S. aureus and daptomycin nonsusceptibility has also been recently described. We report that among three clinical S. aureus isolates which developed vancomycin...

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Identifiers

PMID: 17404001
DOI: 10.1128/AAC.00202-07
PMCID: PMC1891363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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