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Article

Whole-genome sequencing identifies MprF mutations in a genetically diverse population of daptomycin non-susceptible Staphylococcus aureus in Australia.

International journal of antimicrobial agents - 1 May 2024

Lim Candice, Coombs Geoffrey W, Daley Denise A, Shoby Princy, Mowlaboccus Shakeel

Abstract excerpt

OBJECTIVES: Daptomycin is one of the few last-line antimicrobials available for the treatment of multidrug-resistant Staphylococcus aureus infections. An increasing number of daptomycin non-susceptible S. aureus infections has been reported worldwide, including Australia. Resistance to daptomycin is multifactorial and involves chromosomal mutations in genes encoding proteins involved in cell membrane and cell...

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Aminoacyltransferases
Australia
Daptomycin
Drug Resistance, Multiple, Bacterial
Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Staphylococcal Infections

Staphylococcus aureus

Whole Genome Sequencing

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PMID: 38494147
DOI: 10.1016/j.ijantimicag.2024.107144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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