Back to search

Article

Genetic profile of MRSA and MSSA clinical isolates with daptomycin MIC > 1 mg/L

2024-01-30

Abstract excerpt

Daptomycin is one of the last therapeutic resources for multidrug-resistant gram- positive bacteria. Despite its structural similarities with glycopeptides, its mechanisms of action and resistance are different, and in some respects are not completely understood. Mutations in several genes have been associated to daptomycin resistance, especially in mprF, walkR, rpoB and rpoC, but their role and importance remain...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e4f23915-3c6f-5469-8383-bb008836a0ff
DOI
10.20944/preprints202401.2127.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic profile of MRSA and MSSA clinical isolates with daptomycin MIC > 1 mg/LDOI 10.20944/preprints202401.2127.v1
Whole-genome sequencing identifies MprF mutations in a genetically diverse population of daptomycin non-susceptible Staphylococcus aureus in Australia.Semantic proximity
Daptomycin Resistant Staphylococcus aureus Clinical Strain With Novel Non-synonymous Mutations in the mprF and vraS Genes: A New Insight Into Daptomycin ResistanceSemantic proximity
Daptomycin and vancomycin heteroresistance revealed among CC5-SCCmecII MRSA clone and in vitro evaluation of treatment alternatives.Semantic proximity
Antimicrobial resistance in methicillin-resistant staphylococcus aureusSemantic proximity
Investigating a possible link between antiseptic treatment and the increased occurrence of daptomycin-resistant Staphylococcus aureus.Semantic proximity
Characterization of genetic changes associated with daptomycin nonsusceptibility in Staphylococcus aureus.Semantic proximity
A Daptomycin Resistance-Conferring cls1 I269T Mutation in Enterococcus faecium and its Global Prevalence.Semantic proximity
Daptomycin selects for genetic and phenotypic adaptations leading to antibiotic tolerance in MRSA.Semantic proximity
Genomic Insights Into Last-Line Antimicrobial Resistance in Multidrug-Resistant Staphylococcus and Vancomycin-Resistant EnterococcusSemantic proximity
In vivo development of daptomycin resistance in vancomycin-susceptible methicillin-resistant Staphylococcus aureus severe infections previously treated with glycopeptides.Semantic proximity
Single nucleotide polymorphism leads to daptomycin resistance causing amino acid substitution-T345I in MprF of clinically isolated MRSA strains.Semantic proximity
A novel mutation in the vraS gene of Staphylococcus aureus contributes to reduce susceptibility against daptomycin.Semantic proximity
Select a neighboring publication to make it the new centre.