Article
Characterization of a daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus strain in a patient with endocarditis.
Antimicrobial agents and chemotherapy - 1 Sept 2007
Julian Kathleen, Kosowska-Shick Klaudia, Whitener Cynthia, Roos Martin, Labischinski Harald, Rubio Aileen, Parent Leslie, Ednie Lois, Koeth Laura, Bogdanovich Tatiana, Appelbaum Peter C
Abstract excerpt
We analyzed the emergence of daptomycin nonsusceptibility in a patient with persistent vancomycin-intermediate Staphylococcus aureus (VISA) bacteremia. The daptomycin-nonsusceptible VISA's cell wall demonstrated a reduction in muramic acid O-acetylation, a phenotypic parameter not previously repo...
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