Article
Expression and characterization of the Na+/H+ exchanger in the mammalian myocardium.
Molecular and cellular biochemistry - 1 Aug 2007
Coccaro Ersilia, Mraiche Fatima, Malo Mackenzie, Vandertol-Vanier Heather, Bullis Bonnie, Robertson Murray, Fliegel Larry
Abstract excerpt
We examined two expression systems for studying the Na(+)/H(+) exchanger in the mammalian myocardium. Mammalian NHE1 with a hemagglutinin (HA) tag and was cloned behind the alpha myosin heavy chain promoter. Transgenic mice were made with wild type NHE1 protein or with a hyperactive NHE1 protein mutated at the calmodulin-binding domain. Three lines of transgenic mice were made of each cDNA with expression levels...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
